The Buriki One Characters Gai Tendo, Rob Python, Jacques Ducalis, Seo Yong Song, Takato Saionji, Payak Sitpitak, Song Xuandao, Patrick Van Heyting, Akatsuki-Maru, Ryo Sakazaki, Ivan Sokolov, Silber.

Gai Tendo - The lead protagonist, a 17-year-old fighter who uses a self-styled martial art. He has been training by himself at Okinawa ever since graduating middle school. Character voiced by Nobuyuki Hiyama.[6]
Rob Python - A 35-year-old super heavyweight boxer residing in LA. Character voice (CV): Kōji Ishii[7]
Jacques Ducalis - A 32-year-old open-weight Gold medalist and current Director of the French judo Society. CV: Eiji Tsuda[8]
Seo Yong Song - An 18-year-old taekwondo master who was the Middleweight champion in the World Taekwondo Championship during the previous year. Currently attending college with a major in quantum physics. CV: Jun Hashimoto[9]
Takato Saionji - A 17-year-old private high school student from Kyoto who has thoroughly mastered aikido with help from his grandfather, Takayuki. CV: Eiji Yano[10]
Payak Sitpitak - A 40-year-old Muay Thai ranker who is the currently the Top Welterweight athlete in the Muay Thai circuit. CV:Atsushi Yamanishi[11]
Song Xuandao - A 70-year-old tai chi master who is well known within the Chinese fighting world. CV: Keiichiro Sakagi[12]
Patrick Van Heyting - A 37-year-old popular pro wrestler from the Netherlands. CV: Franky Nakamura[7]
Ivan Sokolov - A 27-year-old freestyle wrestler and a 191-pound class Gold Medalist. Despite his rough style, he has won against his opponents due to his technical skills. CV: Hiroyuki Arita[13]
Akatsuki-Maru - A 28-year-old sumo wrestler who currently holds the title of Sekiwake.[a] CV: Eiji Yano[14]
Ryo Sakazaki - The 32-year-old instructor of the Kyokugen School of karate. Originally the main character from the Art of Fighting series. CV: Masaki Usui.[15]
Silber - The final boss in the game. A one-eyed martial artist from Germany who uses his own style of karate. Although Silber has never officially competed in a fighting tournament, he has been sighted in numerous parts of the world over the past 30 years, fighting against many well-known martial artists. Silber is a computer-only character initially and only becomes a controllable character after the computer-controlled Silber is defeated by the player with each of the other characters. CV: Hiroyuki Arita[16]