I think Mastodon would have a lot less of it's potential as a platform stifled if libtards like the ones at meow.social didn't keep absolutely gargantuan domain-level blacklists, that prevent people who would get along just fine from communicating, based on the assumption that all users from a particular instance are nazis or something.

A friend of mine tried to migrate away from Twitter, and gave up as soon as he realized he had to be on a specific server just to talk to me. Tried to hold his hand through it but he lost interest by that point. Most people have higher expectations for a platform like this to be more unified, and the freedom to shut out whoever you please as the webmaster of your own instance comes at a price.