Denuvo is now making its way over to the Switch, apparently.

Given how often Nintendo likes to squeeze every ounce of performance from the console in question for their games, I doubt they'll actually end up using Denuvo because it has a performance penalty. Even if done "correctly" there will still be a performance hit as Denuvo is still heavy.

The more likely case is that third parties use Denuvo on the Switch. Also, don't fear, if the games aren't cracked, there is a good chance they will be freed from Denuvo eventually because Denuvo requires an ongoing license per-game for a company to use. You won't get to play a game right when it comes out on emulator, but give it a year or two and it'll probably be fine.

Given how large and dedicated the Nintendo homebrew/emulation scene is, I wouldn't be surprised if there is a way to bypass this in the future anyway. It could be something as weird as drilling a hole through a chip on the motherboard (shoutout to the Xbox boys).