C. P. McCord and F. P. Allen (J. Exp. Zool. 23, 207–224; 1917) reported that a crude acetone extract of bovine pineal glands fed to Rana pipiens tadpoles caused such a pronounced lightening of their skins that the larger viscera were visible through the dorsal body wall. The tadpoles' transparency varied according to the concentration of pineal extract in the water in which they were swimming.

@hideki the things people did in 1917 after reading old gods fiction and got published in journals. If a critical mind can't advance the sciences, derangement will.
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@chuculate "You know, i have this extract of bovine pineal gland laying around in my lab, i'm sure interesting stuff is going to happen if i feed it to these tadpoles!"

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@hideki So hypnotoad was born but the world was not ready to know.
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