@matrix I actually saw a fangame that did this
Rival: Are you a boy or a girl?
[Dialogue choice with "No" for both options]
Rival: Oh... Yeah, same.
Kinda interesting way to introduce the player and rival as non-binary but it felt too heavy handed. Having "Both" and "Neither" as options instead of two "No"'s would have worked better, and been funnier. Then the devs could have even referenced it later, by having the character referred to as bigender or agender based on what the player picked. It would have been a lot better that way.