It's already confirmed that Blue Protocol will have anti-cheat (Xigncode) but people don't understand what stops mods in UE4 games is a Pak signature lock. When the UE4 version of BnS was released, cosmetic mods worked completely fine while the anti-cheat was enabled. I was also able to use mods with the anti-cheat on in the UE3 version. All UE games have native mod support unless the developers put in a lock that doesn't let the game launch when it starts reading the Mod folder. The Mod folder is manually placed into the Paks. Later on, the devs did input a signature lock because the game is built like horseshit, with many things being client side instead of server side.
So the lock was issued as a poorly done bandage to stop cheating, namely people adjusting skill GCDs and the in-game built in macro (Simple Mode).
I saw a thread on the Reddit of people saying BP will never have mods due to the anti-cheat. This is simply false, retarded, and misinformation. lol
The one person in the entire thread that was actually correct saying the game will have mods was of course down voted.
Now if there is a signature lock on the Pak files, that's a whole different issue that would need to be bypassed. Bypasses are enabled via plugins in the game's folder that contains the executable.
TL;DR: Anti-cheat DOES NOT automatically prevent cosmetic mods.
If I'm able to get an invite to the global beta, I will be able to tell if there is a signature lock.