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Of the six types of PFAS tested, perfluorooctanoic acid (PFOA)—once commonly used in nonstick pans and recently deemed hazardous by the EPA—was by far the most impactful. Despite its small uptake, PFOA altered the expression of almost 600 genes—no other compound altered more than 147. Specifically, PFOA decreased the expression of genes involved in synaptic growth and neural function.

Altogether, the six compounds caused changes in biological pathways involved in hypoxia signaling, oxidative stress, protein synthesis and amino acid metabolism, all of which are crucial for neuronal function and development.

Eleven of the genes were found to express the same way, either more or less, to all six compounds. One of the genes that was consistently downregulated was mesencephalic astrocyte-derived neurotrophic factor, which is important for the survival of neuronal cells and has been shown to reverse symptoms of neurodegenerative diseases in rats. One of the genes consistently upregulated was thioredoxin-interacting protein, which has been linked to neuronal cell death.

https://phys.org/news/2025-01-scientists-genes-affected-pfas-neurotoxicity.html

@astian

How will one enable the VPN in the browser or is it a seperate install ?

" Lesbian DEI LAFD Deputy Chief Slammed After Blaming Fire Victims for Being in ‘Wrong Place’" Stupid is as Stupid does!



https://www.breitbart.com/politics/2025/01/12/lafd-deputy-chief-slammed-after-blaming-fire-victims-for-being-in-wrong-place/#:~:text=Breitbart News Here-,LAFD Deputy Chief Slammed After Blaming Fire Victims for Being in ‘Wrong Place’,-AP Photo/Ethan
#BigPharma Continues to Hide the Truth

While the #FDA and #CDC continue to extol the benefits of the Covid vaccines, they have ignored a growing body of evidence that these products can also be harmful.

#Covid19Vaccines
https://ow.ly/Tiq450UFh8O
There's a reason for that...They told us their goals. They have a History of Problem - Reaction - Solution (PRS). It's not just a Slogan.

They Create the Problem, To Solicit the Reaction, To be the Solution that nobody asked for, or wanted.

Consider all that we've been learning about the Corrupted "Intelligence" Agencies, and the Corrupted and Treasonous Government Officials, being Protected. The same names keep coming up. The criminals Keep Investigating themselves.

How many more LIES must "they" be caught in, before Everyone starts to question...

Question Everything. It's Always about Covert Political Agendas, Manipulation, and Revoking/Surrendering Freedoms...It's all connected.

These fires are unprecedented. Santa Ana Winds in January is unprecedented. That they're expecting even More Santa Ana Winds in January is unprecedented.

The fact that so many unprecedented things are transpiring, means that unprecedented things are transpiring to make them happen...There are No Coincidences.

"As devastating wildfires once again consume California’s landscapes, a growing number of skeptics are pointing to an eerie coincidence: the fires are burning in regions earmarked for major redevelopment under the controversial “SmartLA 2028” initiative.

Critics allege that these fires might not be mere acts of nature but intentional acts to fast-track a dystopian agenda where artificial intelligence governs daily life."

https://www.thegatewaypundit.com/2025/01/california-wildfires-ignite-shocking-theories-claiming-fires-were/

I finished a replay of Shadow Warrior (2013) recently. It still holds up great and is a lot of fun. For those who haven't played it or want to know how the Linux version runs here is a review I put up:

gamespot.com/shadow-warrior/us

It is available DRM free on GOG and has a native Linux version. It's also 90% off until Jan 18:

gog.com/en/game/shadow_warrior

The first postmarketOS edge images with systemd are now available, lots more are building as of writing!

See the updated edge blog post for more information:
postmarketos.org/edge/2025/01/

Huge thanks to everybody who has been involved in making this possible! :ablobcatheartsqueeze:

Mark Zuckerberg admitted on Joe Rogan that the Biden admin pressured Meta to censor true information during COVID — saying it likely "violated the law."

Zuck described officials calling Meta employees, yelling, cursing, and threatening consequences if certain content wasn’t removed.

Yet, despite knowing this, Meta didn’t join the Missouri v. Biden lawsuit challenging government censorship or file its own. Worse, Meta built a special portal for the White House to flag posts for removal.

https://reclaimthenet.org/mark-zuckerberg-criticizes-biden-admin-over-covid-censorship-on-joe-rogan

The call for presentations Early Adopter #Tech Summit will close is less than 48 hours. Please consider submitting a talk about #opensource & #openSUSE before the #CfP closes. events.opensuse.org/

Mark Zuckerberg Falsely Claims “You Can’t Yell ‘Fire’ in a Crowder Theater” To Justify Covid Censorship

https://reclaimthenet.org/mark-zuckerberg-defends-covid-censorship-using-flawed-legal-argument

Heya folks! We have a Contributor Roundup for you today, detailing what our wonderful contributors have been up to lately! Check it out here, on our forum: discuss.getsol.us/d/11271-cont

#Solus #Linux #OpenSource #FOSS

- Evan

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Mainly gaming/nerd instance for people who value free speech. Everyone is welcome.